Comparison of Efficacy and Safety between First and Second Generation Drug-eluting Stents

Comparison of Efficacy and Safety between First and Second Generation Drug-eluting Stents in Patients with Stable Coronary Artery Disease: A

Single-center Retrospective Study

Ru Liu;Run-Lin Gao;Jin-Qing Yuan;Fei Xiong;Yuan Wen;Yuan-Liang Ma;Yi Yao;Zhan Gao;Bo Xu;Yue-Jin Yang;Shu-Bin Qiao

【期刊名称】《中华医学杂志（英文版）》 【年(卷),期】2017(130)014

【摘要】Background:Lots of trials demonstrate that second-generation drug-eluting stents (G2-DES),with their improved properties,offer significantly superior efficacy and safety profiles compared to first generation DES (Gl-DES) for patients with coronary artery disease (CAD) receiving percutaneous coronary intervention (PCI).This study aimed to verify the advantage of G2-DES over G1-DES in Chinese patients with stable CAD (SCAD).Methods:For this retrospective observational analysis,2709 SCAD patients with either G1-DES (n =863) or G2-DES (n =1846) were enrolled consecutively throughout 2013.Propensity score matching (PSM) was applied to control differing baseline factors.Two-year outcomes,including major adverse coronary events as well as individual

events,including

lesion

target

vessel-related

myocardial

vessel

infarction,target revascularization (TLR),target

revascularization,and cardiogenic death were evaluated.Results:The