不同剂量丙种球蛋白治疗重症手足口病患儿的疗效分析
余华娟;梁银志
【期刊名称】《中国医药科学》 【年(卷),期】2013(000)013
【摘要】 目的探讨不同剂量的丙种球蛋白治疗重症手足口病患儿的疗效。方法选取2009年3月~2013年3月来院就诊的重症手足口病患儿97例,分为3组。在基础治疗的基础上,A组给予IVIG 0.2 g/(kg·d)治疗;B组予IVIG 1g/(kg·d)治疗。C组予羚羊角粉治疗。结果 A、B两组患者NSS好转、发热缓解、临床治愈时间比较,差异均无统计学意义(P>0.05)。A、B两组与C组比较,NSS好转、发热缓解、临床治愈时间比较,差异均有统计学意义(P<0.05)。A、B两组治疗10 d后复查脑脊液及心电图正常和异常率比较,差异均无统计学意义(P>0.05)。结论及早使用IVIG对手足口病患儿疗效显著;使用大、小剂量IVIG治疗重症手足口病疗效相近。%Objective To study the curative effect of children with different dose of gamma globulin in the treatment of severe hand-foot-mouth disease. Methods 97 cases in the hospital with severe hand foot and mouth disease in,from 2009 March to 2013 March were divided into 3 groups.On the basis of conventional treatment, A group was given IVIG 0.2g/(kg .d) treatment;group B was treated with IVIG 1g/(kg .d) treatment.C group was treated with antelope horn powder. Results NSS improving, fever,alleviate clinical cure time comparison between A and Bgroup,the difference
was not statistically significant(P>0.05).But NSS