三拗片治疗稳定期慢性阻塞性肺疾病的临床疗效研究
张伟;田梅;张才擎;郭忠良;何翔;孙辉
【期刊名称】《中国全科医学》 【年(卷),期】2016(019)010
【摘要】Objective To investigate the clinical efficacy of San′ao tablets on stable chronic obstructive pulmonary disease(COPD). Methods From May to Aguster in 2014,we enrolled 279 patients with stable COPD who received treatment in the Affiliated Hospital of Shandong University of Traditional Chinese Medicine( n = 78),Shandong Province Qianfoshan Hospital(n = 64),East Hospital Affiliated to Tongji University( n = 64),and Shanghai Pulmonary Hospital Affiliated to TongJi University( n = 73 ) . According to GOLD 2014,we divided the patients into A,B,C,D group. Using central randomized method,we divided each group into observation group(XE,X represents A,B,C,D)and control group(XC). Each control group was administrated with western medicine conventional treatment,and each observation group was administrated with western medicine conventional treatment plus San′ ao tablets, and the treatment lasted for 2 weeks for all the groups. Comparison was made among all the groups in CAT score,SGRQ-C score,6 - min walking distance and the scores of major symptoms,and the adverse reactions of the two groups during treatment were recorded. Results Control group and observation group were significantly different in CAT
score,SGRQ-C score,6 min walking distance and the scores of major symptoms(P < 0. 05). AC group and AE group were significantly different in CAT score and SGRQ-C score(P < 0. 05). BC group and BE group were significantly different in CAT score and the scores of major symptoms(P < 0. 05). CC group and CE group were significantly different in CAT score,SGRQ-C score,6 min walking distance and the scores of major symptoms(P <0. 05). DC group and DE group were significantly different in CAT score and SGRQ-C score(P < 0. 05). Conclusion San′ao tablets have favorable clinical efficacy on stable COPD,and can improve the clinical symptoms,quality of life and capacity for action of patients in each group.%目的：了解三拗片治疗稳定期慢性阻塞性肺疾病（ COPD）的临床疗效。方法于2014年5—8月，选取在山东中医药大学附属医院（n =78）、山东省千佛山医院（n =64）、同济大学附属东方医院（n =64）、同济大学附属上海市肺科医院（n =73）进行治疗的稳定期 COPD 患者279例。根据《慢性阻塞性肺疾病的诊断、治疗与预防的全球策略（2014版）》综合评估标准，将纳入患者分为 A、B、C、D 4组；采用中央随机方法，将各组分为观察组（XE，X 代表 A、B、C、D）和对照组（XC）。各对照组采用西医常规治疗，各观察组在西医常规治疗的基础上加服三拗片，治疗时间均为2周。比较各组治疗前后的 COPD 患者自我评估量表（CAT）评分、COPD 专用改良版生活质量量表（SGRQ-C）评分、6 min 步行距离及主要症状评分，并记录两组治疗期间的不良反应发生情况。结果对照组和观察组治疗前后 CAT 评分、SGRQ-C评分、6 min 步行距离及主要症状评分差值比较，差
异有统计学意义（P <0.05）。其中，AC 组和 AE 组治疗前后 CAT 评分、SGRQ-C评分差值比较，差异有统计学意义（P <0.05）；BC 组和 BE 组治疗前后 CAT 评分、主要症状评分差值比较，差异有统计学意义（P <0.05）；CC 组和 CE 组治疗前后 CAT 评分、SGRQ-C评分、6 min 步行距离、主要症状评分差值比较，差异均有统计学意义（P <0.05）；DC 组和 DE 组治疗前后 CAT 评分、SGRQ-C评分差值比较，差异有统计学意义（P <0.05）。结论三拗片治疗稳定期 COPD 的临床疗效较好，对不同分组患者的临床症状、生活质量及活动能力均有一定程度的改善作用。 【总页数】3页(1204-1206)
【关键词】肺疾病,慢性阻塞性;中西医结合疗法;三拗片;治疗结果 【作者】张伟;田梅;张才擎;郭忠良;何翔;孙辉
【作者单位】250001 山东省济南市，山东中医药大学附属医院肺病科;250001 山东省济南市，山东中医药大学附属医院肺病科;山东省千佛山医院呼吸科;同济大学附属东方医院呼吸科;同济大学附属东方医院呼吸科;同济大学附属上海市肺科医院肺内科 【正文语种】中文 【中图分类】R563.9 【文献来源】
https://www.zhangqiaokeyan.com/academic-journal-cn_chinese-general-practice_thesis/0201255874042.html 【相关文献】
1.中西医联合治疗稳定期慢性阻塞性肺疾病的临床疗效观察 [J], 黎宝红; 邓哲彤;
三拗片治疗稳定期慢性阻塞性肺疾病的临床疗效研究
