肝细胞癌组织中己糖激酶-2蛋白的表达及临床意义
黄尧;黄新辉;黎蕴通;邢晓华;王英超;曾永毅;曾金华;刘小龙;刘景丰
【期刊名称】《中华消化外科杂志》 【年(卷),期】2017(016)002
【摘要】Objective To investigate the expressions of hexokinase 2 (HK2) in tissues of hepatocellular carcinoma (HCC) and adjacent tissues,and its relationships with the clinicopathologic factors of HCC and prognosis of patients.Methods The retrospective cohort and case-control study was conducted.The clinicopathological data of 204 patients with HCC who were admitted to the First Affiliated Hospital of Fujian Medical University from August 2010 to January 2013 were collected.The expressions of HK2 in cancer tissues and adjacent tissues were detected using Western blot.Observation indicators:(1) the expressions of HK2 in cancer tissues and adjacent tissues;(2) relationship between the expression of HK2 in cancer tissues and clinicopathologic factors;(3) risk factors affecting tumor recurrence and metastasis after radical resection of HCC;(4) relationship between the expression of HK2 and prognosis of patients.Follow-up using outpatient examination and telephone interview
was
performed
up
to
December and
31,2015.Imaging
computed
examination,laboratory examination emission
tomography (ECT) examination were applied to patients once every 2 months within 1 year postoperatively and once every 3 months after 1
肝细胞癌组织中己糖激酶-2蛋白的表达及临床意义
