负荷多普勒超声技术评价川崎病患儿左心功能的临床研究
王策;姚翠翠;于宪一;周雅娟
【期刊名称】《中国小儿急救医学》 【年(卷),期】2008(015)006
【摘要】Objective To explore the value of dipyridamole stress echocardiography in assessing the left ventricular function reserve in the children with Kawasaki disease.Methods The study population consisted of 21 patients with a history of Kawasaki disease and they all had
coronary
artery
lesions to
that the
were
determined by
by
echocardiography.According findings 99mTC-MIBI
imaging,the patients were categorized into 2 groups:group A of abnormal 99mTC-MIBI imaging distribution(14 patients) and group N of normal distribution(7 patients).And their left ventricular ejection fraction(LVEF),cardiac index(CI),pre-injection period/left ventricular ejection time(PEP/LVET),fraction shortening(FS),the early-diastolic peak transmitral velocity(Emax) and peak late diastolic transmitral velocity(Amax) were measured before and after injection of dipyridamole.Results Before dipyridamole stress,there was no significant difference in every index between group A and group N.And after dipyridamole
stress,CI
of
group
A
decreased
significantly
(P<0.05);PEP/LVET of group A increased significantly (P<0.05),and one hour after dipyridamole stress they recovered to the normal
level.Conclusion For the children with abnormal distribution of 99Tcm-MIBI
imaging,their
left
ventricle
function
reserve
was
attenuated.Dipyridamole stress echocardiography is a simple and safe way for evaluating cardiac function of the patients with Kawasaki disease,and
suitable
for
continuous
assessment
of
cardiac
function,which is helpful for follow-up.%目的 探讨双嘧达莫负荷多普勒超声技术在川崎病患儿左心储备功能评价方面的临床应用价值.方法 选择超声检查均提示有冠状动脉增宽的川崎病患儿21例,根据99Tcm-甲氧基异丁基异腈心肌断层扫描检查结果 将患儿分为2组,核素分布稀疏组(A组)14例,核素分布正常组(N组)7例.分别于双嘧达莫负荷前后测量左室射血分数(LVEF)、心脏指数(CI)、射血前时间/左室射血时间(PEP/LVET)、短轴缩短率(FS)、二尖瓣环处舒张早期最大峰值流速(Emax)及舒张晚期最大峰值流速(Amax).结果 负荷试验前,A组与N组各项指标比较差异无显著性(P>0.05).负荷后,A组CI明显降低(P<0.05);PEP/LVET明显增高(P<0.05).负荷后1?h时,A组与N组CI和PEP/LVET恢复到负荷前水平.结论 心肌断层扫描核素分布异常的川崎病患儿左室收缩储备能力下降.双嘧达莫负荷超声心动图技术操作简便、安全,可连续性评价患儿的心功能,便于随访. 【总页数】3页(528-530)
【关键词】川崎病;负荷超声心动图;双嘧达莫;左心功能 【作者】王策;姚翠翠;于宪一;周雅娟
【作者单位】110004,沈阳,中国医科大学附属盛京医院儿内科;110004,沈阳,中国医科大学附属盛京医院儿内科;110004,沈阳,中国医科大学附属盛京医院儿内
科;110004,沈阳,中国医科大学附属盛京医院儿内科 【正文语种】中文 【中图分类】R72 【文献来源】
https://www.zhangqiaokeyan.com/academic-journal-cn_chinese-pediatric-emergency-medicine_thesis/0201235812049.html 【相关文献】
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负荷多普勒超声技术评价川崎病患儿左心功能的临床研究
