Association of Source of Memory Complaints and Increased Risk of Cognitive Impairment and

Association of Source of Memory Complaints and Increased Risk of Cognitive Impairment and Cognitive Decline:A Community-Based Study

Xue-Mei Qi;Lin Gu;Hui-Dong Tang;Sheng-Di Chen;Jian-Fang Ma

【期刊名称】《中华医学杂志（英文版）》 【年(卷),期】2018(131)008

【摘要】Background:Memory complaint is common in the elderly.Recently,it was shown that self-report memory complaint was predictive of cognitive decline.This study aimed to investigate the predictive value of the source of memory complaints on the risk of cognitive impairment and cognitive decline in a community-based cohort.Methods:Data on memory complaints and cognitive function were collected among 1840 Chinese participants (aged ≥55 years old) in an urban community at baseline interview and 5-year follow-up.Incident cognitive impairment was identified based on education-adjusted Mini-Mental State Examination score.Logistic regression model was used to estimate the association between the source of memory complaints and risk of cognitive impairment conversion and cognitive decline,after adjusting for covariates.Results:A total of 1840 participants were included into this study including 1713 normal participants and 127 cognitive impairment participants in 2009.Among 1713 normal participants in 2009,130 participants were converted to cognitive