多囊卵巢综合征患者抗苗勒氏管激素、睾酮r和胰岛素抵抗
相关性的临床研究
万启军;张颖;杨悌
【期刊名称】《中国血液流变学杂志》 【年(卷),期】2017(027)003
【摘要】Objective To explore the relationship between anti-Müllerian hormone (AMH), testosterone (T), insulin resistance (IR) levels in patients with polycystic ovary syndrome (PCOS). Methods The serum AMH, T, insulin (Ins) and fasting blood glucose (FBG) levels were determined in 78 patients with PCOS and 60 controls by electrochemiluminescence
immunoassay
and
chemiluminescence
immunoassay and HOMA-IR were calculated and compared analysis was done. Results The serum AMH and T levels in patients with PCOS were significantly higher than those of controls (P all<0.01). The FBG, fasting Ins and HOMA-IR levels in patients with PCOS were significantly higher than those of controls (P<0.05, P<0.05, P<0.01). Conclusion There is close relationship between occurrence and development of PCOS and increased AMH level, hyperandrogenism and IR.%目的 探讨多囊卵巢综合征(polycystic ovary syndrome,PCOS)患者抗苗勒氏管激素(anti-Müllerian hormone,AMH)、睾酮(testosterone,T)和胰岛素抵抗(insulin resistance,IR)相关性的临床研究.方法 电化学发光法和化学发光法测定78例PCOS患者和60名正常对照组血清AMH、T、胰岛素(insulin,Ins)和空腹血糖
(fasting blood glucose,FBG)水平,从而计算稳态型胰岛素抵抗指数(homeostasis model assessment for insulin resistance index,HOMA-IR),并进行对比性分析.结果 PCOS患者血清AMH和T水平显著高于正常对照组(P均<0.01);PCOS患者FBG、空腹Ins、HOMA-IR显著高于正常对照组(P<0.05,P<0.05,P<0.01).结论 PCOS的发生和发展与AMH增高、高雄激素、高胰岛素血症和IR密切相关. 【总页数】3页(320-322)
【关键词】多囊卵巢综合征;抗苗勒氏管激素;睾酮;胰岛素抵抗 【作者】万启军;张颖;杨悌
【作者单位】江苏省昆山市中医医院检验科,江苏 昆山 215300;江苏省昆山市中医医院检验科,江苏 昆山 215300;江苏省昆山市中医医院检验科,江苏 昆山 215300
【正文语种】中文
【中图分类】R711.75;R446.6 【文献来源】
https://www.zhangqiaokeyan.com/academic-journal-cn_chinese-journal-hemorheology_thesis/0201231985277.html 【相关文献】
1.多囊卵巢综合征患者血清抗苗勒氏管激素水平与胰岛素抵抗及雄激素的相关性研究 [J], 杨毅
2.多囊卵巢综合征患者血清抗苗勒氏管激素水平与胰岛素抵抗及雄激素的相关性研究 [J], 杨毅[1]
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多囊卵巢综合征患者抗苗勒氏管激素、睾酮r和胰岛素抵抗相关性的临床研究
