内镜窄带成像技术诊断胃黏膜肠上皮化生的临床应用价值
刘变英;王颖;雷宇锋;李小会;赵文婕;王选桐
【期刊名称】《中华消化杂志》 【年(卷),期】2009(029)005
【摘要】Objective To investigate the morphologic features of gastric intestinal
metaplasia
(IM)using
narrow
band
imaging(NBI)endoscopy,and its feasibility and accuracy for diagnosis of IM
combined
with
histopathology.Methods
The
endoscopic
examination was performed on 80 patients and suspected lesions associated with IM was further observed by NBI combined with magnifying endoscopy.The biopsy specimens were obtained from regions containing light blue crest(LBC)or non-LBC mucosa for pathological examination,and the results were analyzed.Results In 80 patients examined with NBI,IM was pathologically confirmed in 65 patients.Of which LBC was seen in 61 patients with a sensitivity of 94%and a specificity of 95%.In a total of 94 specimens obtained from LBC region,86 had histological evidence of IM with a positive predictive value of 9 1.49%.There was no evidence of IM in 79 out of 94 specimens obtained from non-LBC region of patients with or without LBC with a negative predictive value of 84.04%.The results indicated that the detective rate of IM could be increased if biopsy specimen was obtained from LBC region with help of NBI endoscopy(P＜0.05).Conclusions It has
内镜窄带成像技术诊断胃黏膜肠上皮化生的临床应用价值
