Pancreatic neuroendocrine tumor liver metastasisin a patient with previously diagnosed pan

Pancreatic neuroendocrine tumor liver metastasisin a patient with previously diagnosed pancreatic adenocarcinoma: an unexpected diagnosis

Mário

Fontes-Sousa;Helena

Magalh?es;Bianca

Machado;Olga

Sousa;Manuela

Machado

【期刊名称】《癌症转移与治疗（英文版）》 【年(卷),期】2018(004)001

【摘要】Locally advanced pancreatic carcinoma has an usually poor prognosis despite multimodal approaches and sequential chemotherapy. The authors present a case of a long-term survivor with stage III pancreatic adenocarcinoma achieving partial response after a multimodal approach including local and systemic treatments. However, three years after diagnosis and amidst several episodes of cholangitis, hepatic metastasis were suspected. Despite pancreatic adenocarcinoma being the obvious culprit for metastization, a hepatic biopsy was considered at that time given a stable primary disease and presenting three years since the initial diagnosis. At this point, a biopsy could have specific diagnostic, prognostic and therapeutic implications and after it was performed, an unexpected diagnosis of pancreatic neuroendocrine tumor was made. Therefore, we urge clinicians to consider hepatic biopsy in similar cases- generally when it may change prognosis and treatment strategies - and perform histological confirmation of

metastatic disease whenever feasible, even if the answer may seem obvious at first impression. 【总页数】6页(69-74) 【关键词】

【作者】Mário Fontes-Sousa;Helena Magalh?es;Bianca Machado;Olga Sousa;Manuela Machado

【作者单位】Department of Medical Oncology, Portuguese Oncology Institute-Porto, Porto 4200-072, Portugal;Department of Medical Oncology, Portuguese Oncology Institute-Porto, Porto 4200-072, Portugal;Pathology Department, Portuguese Oncology Institute-Porto, Porto 4200-072, Portugal;Radioncology Department, Portuguese Oncology Institute-Porto, Porto 4200-072, Portugal;Department of Medical Oncology, Portuguese Oncology Institute-Porto, Porto 4200-072, Portugal 【正文语种】英文 【中图分类】 【文献来源】

https://www.zhangqiaokeyan.com/academic-journal-cn_cancer-metastasis-treatment-english_thesis/0201227374598.html 【相关文献】

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