非霍奇金淋巴瘤与乙型肝炎病毒感染关系的临床研究
任苑蓉;熊竹娟;敬小梅;吴萍;李力;张智慧
【期刊名称】《肿瘤预防与治疗》 【年(卷),期】2013(026)002
【摘要】Objective: To study the relationship between non-Hodgkin' s lymphoma( NHL) and HBV infection in Sichuan area through retrospective analysis. Method: Serum markers of HBV were measured with ELISA technique in 160 NHL patients, 160 healthy people and 160 patients with other kinds of cancer ( except primary hepatocellular carcinoma ) in the corresponding hospitalized period, and the results were compared. Result: HBV infection rates of 160 NHL patients were significantly higher than that in two con trol groups(P <0. 05) . HBV infection rates at Ⅲ,Ⅳ stage were significantly higher than that at stage Ⅰ,Ⅱ(P <0. 05)in 160 NHL pa tients. Conclusion: The rate of HBV infection in NHL patients is significantly higher than that in healthy people and those with other kinds of cancer in Sichuan area. HBV infection may play a role in the development of NHL.%目的:探讨四川地区非霍奇金淋巴瘤(NHL)与乙型肝炎病毒(HBV)感染的关系.方法:对160例NHL患者临床资料进行回顾性分析,应用ELISA方法测定确诊NHL时患者的乙型肝炎病毒两对半情况,并随机抽取同期住院的160例其他恶性肿瘤患者(排除原发肝细胞肝癌),160例健康体检者作为对照进行比较.结果:160例NHL患者伴HBV感染者39例(占45%),其他恶性肿瘤患者HBV感染者19例(占11.9%),健
康体检者HBV感染者17例(占10.6%),与肿瘤对照组和健康对照组相比,NHL组HBV感染率高于该两组,差异有统计学意义(P<0.05).而两对照组间比较,差异无统计学意义(P＞0.05).Ⅲ期和IV期NHL患者HBV感染率明显高于I期和II期患者,差异有统计学意义(P<0.05).结论:四川地区NHL患者中HBV感染率高于一般人群和非原发性肝细胞肝癌肿瘤患者,HBV感染与NHL发病有一定相关性.
【总页数】3页(72-74)
【关键词】恶性淋巴瘤;乙型肝炎病毒
【作者】任苑蓉;熊竹娟;敬小梅;吴萍;李力;张智慧 【作者单位】四川省肿瘤医院,淋巴瘤科,成都,610041 【正文语种】中文
【中图分类】R733.4;R730.231+.3 【文献来源】
https://www.zhangqiaokeyan.com/academic-journal-cn_journal-cancer-control-treatment_thesis/0201236358925.html 【相关文献】
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非霍奇金淋巴瘤与乙型肝炎病毒感染关系的临床研究
