Study on the Early Detection and Clinico—pathologic Staging of Colorectal Cancer in China

Study on the Early Detection and Clinico—pathologic Staging of Colorectal Cancer in China

ZHENGShu;CAIShanrong;等

【期刊名称】《中德临床肿瘤学杂志：英文版》 【年(卷),期】2002(001)002

【摘要】Objective To confim an effective and practicable screening model for early detection of colorectal cancer(CRC),and to modify an ac-ceptable and reasonable staging of CRC for predicting prognosis and to define the therapeutic strategy. Methods Data from 3 case-control studies have been used for selecting the high risk factors of CRC to optimize Sequencing Screening Model (SSM).The fieldwork recalls have been utilized to compare the sensitivity,specificity and Youden Index between the SSMand the optimized one.The 1722 individuals have been used

to

evaluate

the

Optimized

Sequencing

Screening

Model(OPSM).From 1980 to 1995, 1334 cases of CRC pathologically confimed have been analyzed for 3-,5-and 10-year survival rates.All tests were performed at the 0.05 level of significances.Statistical analysis was conducted by using the SPSS 10.0 statistic software. Results A simple questionnaire and RPHA-FOB test as the screening model for early detecting CRC had been proved as an optimized screening model.The sensitivity,specificity and Youden Index of the optimized model were higher than those of SSM.From the 1722 indi-viduals