纤维支气管镜下刷取标本液基细胞学检查在肺癌临床诊断
中的价值
赵焕;郭会芹;张传欣;赵琳琳;曹箭;潘秦镜
【期刊名称】《中华肿瘤杂志》 【年(卷),期】2015(000)006
【摘要】Objective To investigate the value of the liquid?based cytology ( LBC ) of brushing specimens obtained via fiberoptic bronchoscopy for clinical diagnosis of lung cancer. Methods We retrospectively analyzed the LBC cases in our hospital from January 2011 to May 2012, and evaluate its role in the diagnosis of lung cancer. Results The clinical data of a total of 4 380 cases were reviewed and 3 763 of them had histopathological or clinical follow?up results ( including 3 306 lung cancer cases and 457 benign lesion cases) . The sensitivity, specificity, and accuracy of LBC diagnosis for lung cancer were 72. 4%(2 392/3 306), 99.3%(454/457) and 75.6%(2 846/3 763), respectively. Of the 1 992 lung cancer cases diagnosed by brushing LBC, 528 cases(26.5%) were failed to take forceps biopsy and 113 cases(5.7%) showed negative forceps biopsy results. The accurate rate of subtyping of LBC for non?small cell carcinoma and small cell carcinoma was 99.0% (1 487/1 502) (P<0.001).Take the resection histopathology as gold standard, the accurate rates of subtyping squamous cell carcinoma, adenocarcinoma and small cell carcinoma by LBC were 95.6%(351/367), 95.6%(351/367)
纤维支气管镜下刷取标本液基细胞学检查在肺癌临床诊断中的价值
