中国当代医药2024年6月第26卷第18期窑基础医学窑FRD特殊染色技术与液基细胞学检查在宫颈癌前病变筛查中的应用对比刘露晖1李桂宝2银王栾玲1黄凤友1陈新妹3赖珍苗1贺凌云4胡红云1513000513000曰1.广东省英德市人民医院新城门诊部袁广东英德3.广东省英德市人民医院病理科袁广东英德513000曰4.广东省英德市人民医院妇科袁广东英德513000曰2.广东省英德市人民医院科教科袁广东英德[摘要]目的比较FRD和TCT检查在宫颈癌筛查中的应用价值遥方法采取自身对照法袁选取2015年4月耀2024年1月我院妇科门诊的2500例患者袁均行FRD和TCT检查袁FRD或渊和冤TCT结果阳性袁再行阴道镜检查并取宫颈组织活检袁以活检结果为金标准袁评价FRD和TCT筛查的阳性检出率及FRD和TCT的诊断价值遥以灵敏度尧特异性尧误诊率尧漏诊率尧阳性预测率尧阴性预测率为诊断价值指标遥结果2500例患者中袁FRD和TCT的阳性检出率分别为10.32%和9.96%袁两者比较差异无统计学意义渊P跃0.05冤遥FRD和TCT的灵敏度尧特异性尧误诊率尧漏诊率尧阳性预测率及阴性预测比较袁差异均无统计学意义渊P跃0.05冤遥结论FRD和TCT对宫颈癌前病变筛查均具检出效能袁诊断价值相当遥[中图分类号]R737.33[关键词]宫颈癌前病变曰筛查曰叶酸受体介导的宫颈特殊染色曰液基薄层细胞学检测[文献标识码]A[文章编号]1674-4721渊2024冤6渊c冤-0031-04ApplicationcomparisonofFRDspecialstainingtechniqueandthin-prepcytologytestinscreeningofcervicalprecancerouslesionsLIULu-hui1LIGui-bao2银WANGLuan-ling1HUANGFeng-you1CHENXin-mei3LAIZhen-miao1HELing-yun4HUHong-yun11.XinchengClinic,People忆sHospitalofYingdeCityinGuangdongProvince,YingdementofPathology,People忆sHospitalofYingdeCityinGuangdongProvince,Yingde513000,China;2.Divisionof513000,China;3.Depart鄄ScienceandEducation,People忆sHospitalofYingdeCityinGuangdongProvince,YingdeGynecology,People忆sHospitalofYingdeCityinGuangdongProvince,Yingde513000,China513000,China;4.Departmentof[Abstract]ObjectiveTocomparetheapplicationvalueoffolatereceptor-mediateddetection(FRD)andthin-prepcytol鄄ogytest(TCT)incervicalcancerscreening.MethodsByself-controlmethod,fromApril2015toJanuary2024,2500pa鄄tientsinthegynaecologicalclinicofourhospitalperformedwithFRDandTCTexaminationswereselected.WhentheFRDwereevaluated,theparametersweresensitivity,specificity,misdiagnosisrate,misseddiagnosisrate,positivepredictiverate,andnegativepredictiverate.ResultsAmong2500patients,thepositivedetectionratesofFRDandTCTwereor/andTCToutcomeswerepositive,thecervicalbiopsyundercolposcopewasperformed.Thebiopsyresultwassetasthegoldenstandard.ThepositivedetectionrateofFRDandTCTscreeningandthediagnosticvaluesofFRDandTCT10.32%and9.96%,respectively,therewasnosignificantdifferencebetweenthetwogroups(P跃0.05).WithregardtotheandTCTbothobtaintheeffectsofscreeningforcervicalprecancerouslesions,andthediagnosticvalueisequivalent.prepcytologytestsensitivity,specificity,misdiagnosisrate,misseddiagnosisrate,positivepredictiverateandnegativepredictiverateof[Keywords]Cervicalprecancerouslesion;Screening;Folatereceptor-mediatedtumordetection;Liquid-basedthin-theFRDandTCT,therewerenosignificantdifferencesbetweenthetwodetectionmethods(P跃0.05).ConclusionFRD[基金项目]广东省清远市社会发展领域自筹经费科技计划项目渊2015B097冤[作者简介]刘露晖渊1975-冤袁女袁湖南邵阳人袁本科袁副主任医师袁研究方向院妇科肿瘤银约13.2万袁死亡5万[2]袁并有年轻化趋势[3-4]遥宫颈癌有明显的癌前病变期袁而且发展缓慢袁但多数患者就诊时已经处于晚期袁失去了最佳治疗时机袁因此宫颈病预是阻断宫颈癌发展的关键袁能使发病率与死亡率大CHINAMODERNMEDICINEVol.26No.18June2024宫颈癌是妇产科常见的恶性肿瘤[1]袁每年新发病通讯作者院李桂宝渊1963-冤袁女袁湖南祁东人袁主任护师袁研究方向院科研教学及护理变的早期筛查十分重要[5]遥尽早发现癌前病变袁及时干31
FRD特殊染色技术与液基细胞学检查在宫颈癌前病变筛查中的应用对比
