肿瘤休眠的机制及其意义
吴克复;郑国光;马小彤;宋玉华
【期刊名称】《白血病·淋巴瘤》 【年(卷),期】2016(025)003
【摘要】Dormant follicular lymphoma, prostate carcinoma and breast carcinoma are frequently detected by autopsy of non-tumor patients. Dormancy of malignant cells in hematopoietic malignancies is associated with genesis, development and treatment of these diseases. Dormancy is the universally applied strategy by living organism during survival competition. As the in vivo neoplasm, tumor cells keep this property. Recently, much attention has been paid to the mechanisms of tumor dormancy. These studies not only have theoretical significance, provide new ways for the prevention and treatment of tumors, but also help the understanding of \\and provide clues for \medicine\This paper reviewed cellular mechanism of tumor cell dormancy,immunological and vascular regulation of dormant tumors. The clinical significance,application of these mechanisms and direction of further study, which will provide new clues for the treatment of hematopoietic malignancies, were also discussed.%非肿瘤死亡患者尸检常见滤泡性淋巴瘤、前列腺癌、乳腺癌等休眠肿瘤，而血液系统恶性肿瘤细胞的休眠与疾病的发生、发展和治疗密切相关。休眠是生物在生存竞争中普遍采用的策略，作为体内新生物的肿瘤保留了这类
肿瘤休眠的机制及其意义
