艾灸预处理对应激性溃疡大鼠胃黏膜GSH-Px,SOD,MDA
的影响
刘密;常小荣;严洁;易受乡;林亚平;岳增辉;彭艳;崔学军
【期刊名称】《针灸推拿医学（英文版）》 【年(卷),期】2011(009)001
【摘要】Objective:To observe the effects of moxibustion pretreatment on Glutathione Peroxidase(GSH-Px),Superoxide Dismutase(SOD),and Malondialchehyche(MDA)in gastric mucosa of rats with stress ulcer,and to investigate the mechanism of moxibustion pretreatment preventing the oxidized injury of gastric mucosa.Methods:Forty-eight healthy SD rats were randomly allocated into 4 groups,namely control group,model group,acupoint moxibustion group,and non-acupoint moxibustion group.The ulcer model was developed by restraint and water immersion stress,Ulcer index(UI)was calculated with Guth method,and the contents of GSH-Px,and MDA and SOD activity in the gastric tissues were measured with chromatometry method.Results:Compared those in the model group and nonacupoint moxibustion group,moxibustion at Zusanli(ST
36)could
decrease
the
UI(P<0.01)and
MDA(P<0.05)contents,and increase the activity of GSH-Px(P<0.01)and SOD(P<0.05).Conclusion:Pretreatment of moxibustion at Zusanli(ST 36)could promote the recovery of gastric injury in rats induced by restraint and water immersion stress by enhancing the activity of GSH-
艾灸预处理对应激性溃疡大鼠胃黏膜GSH-Px,SOD,MDA的影响
