他克莫司联合糖皮质激素治疗成人特应性皮炎的疗效研究
韦千里;高君;肖文
【期刊名称】《河北医学》 【年(卷),期】2012(018)010
【摘要】目的:探讨他克莫司联合糖皮质激素治疗成人特应性皮炎疗效.方法:将本院近期门诊收治的60例成人特应性皮炎患者随机分两组,对照组30例单行糖皮质激素治疗,实验组30例联合他克莫司,对比两组患者治疗后的脱屑、红斑、毛细血管扩张、皮肤萎缩、丘疹脓疱、色素沉着等皮损积分变化,并统计患者总有效率(显效+有效).结果:两组内比较,治疗后第4周患者各项皮损积分均优于治疗前 (P<0.05);而两组间相比,实验组患者的各项皮损积分明显优于对照组 (P<0.05),且实验组患者的总有效率为93.3%,明显高于对照组的80.0%(p<0.05).结论:应用他克莫司联合糖皮质激素早期治疗成人特应性皮炎,可以显著改善皮损积分变化,有效提高患者的预后.%Objective: To investigate the tacrolimus combined with corticosteroids in the treatment of a-dult atopic dermatitis in the method and curative effect. Method: the recent outpatient hospital treated 60 cases of adult patients with atopic dermatitis were randomly divided into 2 groups, 30 cases in the control group specific glucocorticoid treatment, the experimental group 30 cases combined with tacrolimus, compared two groups of patients after treatment of scaling, erythema, telangiectasia, papules , pustules, skin atrophy, pigmentation and other skin lesions integral change, and statistical total efficiency ( markedly + effective ). Result: of the two
他克莫司联合糖皮质激素治疗成人特应性皮炎的疗效研究
