替吉奥及多西他赛联合奈达铂治疗中晚期食管癌的临床研
究
李伟;方黎;赵宏亮
【期刊名称】《中国实用医刊》 【年(卷),期】2014(000)024
【摘要】Objective To investigate the efficacy and safety of S-1 combined with nedaplatin,do-cetaxel combined with nedaplatin plus concurrent radiotherapy in the treatment of moderate and advanced stages of esophageal cancer. Methods Fifty-six patients with the moderate and advanced stages of esopha-geal cancer were randomly divided into two groups:S-1 combined with nedaplatin,docetaxel combined with nedaplatin plus concurrent radiotherapy. Results The effective rate in the S-1 combined with nedapl-atin group and the docetaxel combined with nedaplatin group was 82. 1% and 85. 7%,the difference was not statistically significant. The main side effects were gastrointestinal
reactions,myelosuppression,radio-active
bronchitis,radioactive esophagitis,phlebitis. Docetaxel combined with nedaplatin had more the heavier myelosuppression,but it could be controlled after treatment. Conclusions Two concurrent chemo-radiation therapy program can be used. S-1 combined with nedaplatin has light toxic effects.%目的：探讨替吉奥+奈达铂、多西他赛+奈达铂方案加同步放疗治疗中晚期食管癌的疗效及不良反应。方法56例中晚期食管癌患
替吉奥及多西他赛联合奈达铂治疗中晚期食管癌的临床研究
