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PROCESS FOR PREPARING TETRAHYDROPYRIDO

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PROCESS FOR PREPARING TETRAHYDROPYRIDO£2,3-3|PYRIMIDINE DERIVATIVES

申请(专利)号: KR19870005798

专利号: KR950004894B1 主分类号: C07D471/04 申请权利人: THE TRUSTEES

OF PRINCETON UNIVERSITY

申请日: 1987-06-05 公开公告日: 1995-05-15

分类号: C07D471/04 发明设计人: TAYLOR, EDWARD

C.;

BEARDSLEY, GEORGE P.; SHIH, CHUAN; PLETCHER, STEPHEN R. 申请国代码: KR

优先权: 19860606 US

871,539

摘 要 附 图:

公开国代码: KR 优先权国家: US

摘 要:

The diastereoisomeric forms of N-(4-[2-(2-amino-4-hydroxy-5,6,7,8-tetrahydropyrido[2,3-d] -pyrimidin-6-yl)ethyl]benzoyl)-L-glutamic acid are antineoplastic agents. The compounds are prepared by separation of the diastereoisomeric form of the

correspondingly protected glutamic derivatives and hydrolytic or

hydrogenolytic removal of carboxylic acid and/or amino protecting groups. 主权项:

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PROCESS FOR PREPARING TETRAHYDROPYRIDO

PROCESSFORPREPARINGTETRAHYDROPYRIDO£2,3-3|PYRIMIDINEDERIVATIVES申请(专利)号:KR19870005798专利号:KR950004894B1主分类号:C07D471/04申请权利人:THETRUSTEESOFPRINCETONUNIVERSITY<
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