贝类镉胁迫功能基因研究进展

贝类镉胁迫功能基因研究进展

高翔;王源

【期刊名称】《中国农业大学学报》 【年(卷),期】2017(022)003

【摘要】贝类对重金属有较强的富集能力和耐受力,说明在贝类体内具有重金属积累、贮存和解毒的特殊机制,可能存在复杂的功能基因应激表达调控网络.近年来,国内外关于贝类镉胁迫功能基因的研究逐渐增多,主要有抗氧化酶、金属硫蛋白和热休克蛋白等,但相较于其它物种鉴定得到的功能基因数量还是太少、功能研究不够系统和深入.随着人们对环境保护和食品安全的重视,伴随着生命科学新技术的不断涌现,相关功能基因的研究也必将不断加深,而这对于更好的认识并掌握细胞生命活动的运作机制、弄清贝类重金属胁迫应激表达通路及分子调控网络,以及准确评价和预测重金属对水环境的影响具有非常重要的意义.%The safety of the sea food largely depends in the level of heavy metals accumulated in the body;which is determined by the content of heavy metals in the aquaculture environment.Cadmium,a highly toxic heavy metal,is a common water pollutant.It is a worldwide risk affecting food and feed safety due to its long biological half-life resulting in accumulation and amplification in the body.Bivalve molluscs are filter-feeding sedentary species,especially prone to the accumulation and concentration of contaminants suggesting the existences of complex stress expression pathways and molecular regulation networks play very important roles in the heavy metal detoxify mechanism.In recent

years,the research on functional genes including antioxidant enzyme,metallothionein,heat shock protein,etc.under cadmium stress is gradually increased.There are still lacks of more systematic and intensive research,new

technology

and

new

methods.However,with

the

development of society and human science,more and more attention is paid on food safety and environment protection and related research also will be deepened,these will eventually enrich our acknowledgement on mechanism of gene expression patterns and regulatory network under cadmium stress condition and provide novel insights into the molecular mechanism of biological monitoring of water pollution. 【总页数】9页(122-130)

【关键词】镉;贝类;功能基因;分子指标;研究进展 【作者】高翔;王源

【作者单位】中国海洋大学海洋生命学院,山东青岛266100;山东省海洋生物研究院,山东青岛266104;山东省海洋生物研究院,山东青岛266104 【正文语种】中文 【中图分类】Q78 【文献来源】

https://www.zhangqiaokeyan.com/academic-journal-cn_china-agricultural-university-journal-social-sciences-edition_thesis/02012932887.html 【相关文献】

1.贝类病害学研究进展：Ⅰ.贝类微生物病学研究 [J], 吴信忠; 潘金培 2.贝类低温胁迫响应机制研究进展 [J], 董莎莎; 聂鸿涛; 闫喜武

3.电感耦合等离子体质谱法测定海洋贝类中镉、铬、铜和铅 [J], 龚倩; 金高娃; 李小蕾; 史永富; 蔡友琼; 顾润润

4.海洋贝类摄取对人体重金属镉沉积的影响及绿藻、硒和锌干预性清排的机制 [J], 林海; 于晓波; 龚桦; 董晓丽; 孙玉梅

5.改性稻壳脱除贝类酶解液中的重金属镉 [J], 张文婷; 陈宏; 刘旭; 靖玉; 孙思阳; 励建荣

以上内容为文献基本信息，获取文献全文请下载