his bleak situation, doctors offered him a little hope: a bone marrow（骨髓）transplant to treat his cancer and an experimental treatment for his HIV. They used this chance to edit the DNA in bone marrow stem cells（干细胞）from a donor before transplanting the cells into the patient.
Specifically, the treatment involved using the gene-editing tool CRISPR-Cas9 to delete a gene known as CCRS, which encodes（给……编码）a protein that HIV uses to get inside human cells. Without the gene, HIV is unable to enter cells. Talking about the gene, lead scientist Deng Hongkui told CNN, “After being edited, the cells - and the blood cells they produce - have the ability to resist HIV infection.” Nineteen months after the treatment, the patient’s leukemia was in complete remission（缓解）and donor cells without CCR5 remained, according to the research paper.
Though the transplant didn’t cure the man’s HIV, it still showed the effectiveness of gene-editing technology, as there was no indication of any unintended genetic changes - a major concern with past gene-editing treatment experiments.
Amesh Adalja, a senior scholar at the Johns Hopkins Center for Health Security in the United States, who was not involved in the study, praised the treatment. “They did a very creative experiment, and it was safe,” he told Live Science. “It should be viewed as a success.”
Deng believes gene-editing technology could “bring a new dawn” to blood - related diseases such as AIDS and sickle-cell anaemia（镰状细胞贫血）. “Thanks to this new technology, the goal of a functional cure for AIDS is getting closer and closer,” he said.
32. The underlined word “bleak” in Paragraph 3 probably means “__________”. A. hopeless B. unstable C. embarrassing D. unique 33. How did the treatment fight against HIV?
A. By identifying and killing HIV. B. By changing the structure of HIV. C. By preventing HIV entering cells. D. By removing a protein HIV feeds on.
34. What is the result of the treatment?
A. Gene-edited cells are able to resist HIV infection. B. The number of cells infected by HIV has decreased.
C. CCR5 and other genes in the patient’s cells are changed.
D. Unintended genetic changes have taken place in the patient’s cells. 35. What can we know about the experiment?
A. It pointed out the problems of gene treatment. B. It provided a new way to cure AIDS patients fully.
C. It could offer a safe treatment for blood-related diseases.
D. It was the first example to use gene-editing tool to treat AIDS. 第二节（共5小题；每小题2分，满分10分） 根据短文内容，从短文后的选项中选出能填入空白处的最佳选项，并在答题卡上将该项涂黑。选项中有两项为多余选项。
Are people less or more happy when they get older? A study in 2018 found that
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people generally become happier and experience less worry after age 50. In fact, it found that by the age of 85, people are happier with their life than they were at 18.
Arthur Stone in the Department of Psychiatry and Behavioral Science at Stony Brook University in New York led the study. His team found that levels of stress were the highest among adults between the ages of 22 and 25. 36
Happiness was the highest among the youngest adults and those in their early 70’s. But the people least likely to report feeling negative emotions were those in their 70’s and 80’s. The survey also found that men and women have similar emotional patterns as they grow older. 37 The researchers also considered possible influences like having young children, being unemployed or being single. But they found that influences like these did not affect the levels of happiness and well-being related to age.
38 One theory is that, as people get older, they become more thankful for what they have and have better control of their emotions. They also spend less time thinking about bad experiences.
39 In another study, people in their 80’s reported the fewest problems with the quality of their sleep. The original goal was to confirm the popular belief that aging is connected with increased sleep problems. 40 But except for that, people reported that they felt their sleep quality improved as they got older. A. So why will happiness increase with age?
B. Researchers surveyed more than 150,000 American adults.
C. At that time, the people were between the ages of 18 and 85. D. Stress levels dropped sharply after people reached their 50’s. E. Happiness is not the only thing that apparently improves with age.
F. The survey did find an increase during middle age, especially in women. G. However, women at all ages reported more sadness, stress and worry than men. 第三部分 语言知识运用（共两节，满分45分）
第一节 完形填空（共20小题；每小题1．5分，满分30分）
阅读下面短文，从短文后各题所给的A、B、C和D四个选项中，选出可以填入空白处的最佳选项，并在答题卡上将该项涂黑。
Five years ago, I took a career risk by leaving my job to work on a ship. My medical friends did their best to persuade me, saying that running away to sea would 41 my career. But after these years working as a junior doctor, I was willing to take the risk.
42 for adventure, I boarded a ship in Singapore with 2,000 passengers and crew. To my __43 , the hospital was well equipped, with an X-ray machine and a blood analyzer. That first voyage was a learning experience, a 44 schedule full of safety drills. There was so much new information to 45 . Even remembering which uniform to wear each day was a 46 . Most confusing, I often forgot to 47 my clock when the ship crossed time zones.
As a doctor, I was 48 for the 600 crew, and I was on call for the entire ship. Far from __49 seasickness and sunburn, I had to deal with other diseases,
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for my patients were wide and varied. The ship’s medical center was 50 a floating emergency room, and we didn’t have a team of specialists on hand for a second 51 . With long and unpredictable hours, it required mental 52 .
As you can guess, many of the passengers were elderly. Heart attacks don’t 53__ geography and emergency evacuations（疏散）were difficult to arrange. I recall one such patient, who was taken off the ship halfway through the Panama Canal. After a 54 ride in an old ambulance, I was relieved that the patient 55 long enough to arrive at the hospital in Panama City.
56 , there were several unexpected benefits to the job. I regularly 57 the passenger facilities（设施）and I even hosted my own table of passengers in the evenings. On rare days off, I __58 as a tour guide on trips ashore. I got to fly over Alaska in a seaplane and watched a ballet in St Petersburg.
Now, I understand being a ship doctor is not a job - it’s a way of 59 . One year at sea became two. I lost my career ambitions, 60 I redefined happiness is a my life. 41. A. block B. build C. ruin D. improve 42. A. Hungry B. Skilful C. Suitable D. Concerned 43. A. shock B. disappointment C. excitement D. relief 44. A. daily B. tight C. strict D. flexible 45. A. take in B. figure out C. search for D. pick over 46. A. training B. risk C. challenge D. choice 47. A. watch B. repair C. check D. set 48. A. powerful B. responsible C. hopeful D. helpful 49. A. treating B. suffering C. escaping D. stopping 50. A. exactly B. particularly C. certainly D. actually 51. A. examination B. consideration C. opinion D. discussion 52. A. comfort B. communication C. toughness D. pressure 53. A. care about B. refer to C. trouble with D. rely on 54. A. relaxing B. boring C. promising D. terrifying 55. A. survived B. struggled C. awoke D. stuck 56. A. Steadily B. Thankfully C. Importantly D. Generally 57. A. cleaned B. fixed C. enjoyed D. protected 58. A. returned B. travelled C. performed D. volunteered 59. A. confidence B. life C. experience D. success 60. A. though B. unless C. but D. or 第二节（共10小题；每小题1．5分，满分15分） 阅读下面短文，在空白处填入1个适当的单词或括号内单词的正确形式，并将答案填写在答题卡相应的位置上。
If you’ve ever ridden public transport, you’ve probably heard snoring（打鼾）and found someone sleeping in the seat across from you. The natural vibration（震动）of buses and subways __61 （make）us feel sleepy, according to a new study in Science Alert.
Why? It’s all about sensory input - information going to your brain. On a bus, your senses give you 62 （continue）and repeating information. For example, the
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air conditioner and engine create constant white noise. Meanwhile, you’re sitting still and your 63 （surrounding）don’t change. The vibrations of the engine are also ongoing. Your brain has almost no new information to process.
Repeating information will be 64 _（ignore）eventually and your brain will enter a low-energy state. The fact that you fall asleep quickly with your eyes 65 （close）on a bus is because your brain gets used to all the repeat.
“When you’re tired, it doesn’t take much time 66 （start） nodding off and we’ve found that the gentle vibrations made by car seats 67 you drive can lull（使放松） your brain and body,” said Stephen Robinson, 68 researcher from the RMIT University in Melbourne, Australia.
Robinson’s team monitored 15 volunteers’ heart rate variability（心率变异性）– a well-known indicator of sleepiness. This line of research can assist in the development of practical and relevant guidelines for limiting 69 （expose）to vibrations in the car industry. Robinson believed that the research could be helpful 70 improving road safety. “We hope that future car seat designs can build in features to disturb this lulling effect and fight vibration-induced（震动引起的） sleepiness,” he said. 第四部分 写作（共两节，满分35分）
第一节 短文改错（共10小题；每小题1分，满分10分） 假定英语课上老师要求同桌之间交换修改作文，请你修改你同桌写的以下作文。文中共有10处语言错误，每句中最多有两处。每处错误仅涉及一个单词的增加、删除或修改。 增加：在缺词处加一个漏字符号（∧），并在其下面写出该加的词。 删除：把多余的词用斜线（＼）划掉。
修改：在错的词下划一横线，并在该词下面写出修改后的词。 注意：
1．每处错误及其修改均仅限一词；
2．只允许修改10处，多者（从第11处起）不计分。
The first foreign language I never learnt was French, but it didn’t go very well. My mother asked our neighbor teach me when I was seven. French wasn’t his native languages, but he used to live in France, so he could speak a little. However, I learnt very little until I didn’t feel it related to my daily life anyway. When I entered into senior high school, my attitude to language learning changed. I decided to learn Latin, that I’ve always been interested in because I want to study law. Learning Latin wasn’t a struggle for myself for this reason. Soon I begin to read classic books in Latin. Read those books opened a window for me to another world or gave me a new point of view on my own world. 第二节 书面表达（满分25分） 假定你是李华，在你校学习汉语的美国交换生Peter发邮件说他想参加你校即将举办的中华经典文学朗诵比赛（Chinese Classics Recital Contest），但不知如何准备，请根据以下要点用英语给他回复。 1．推荐朗诵内容； 2．介绍朗诵技巧； 3．告知注意事项； 4．预祝比赛成功。
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注意：
1．词数100左右；
2．可以适当增加细节，以使行文连贯； 3．开头和结尾已为你写好，不计入总词数。 Dear Peter,
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Yours, Li Hua
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河南省新乡市新乡一中2020届高三英语上学期第一次质量预测试题
