北京地区1359名非糖尿病人群心血管病危险因素与胰岛
素抵抗的关系研究
王淼;赵冬;王薇;刘静;刘军;孙佳艺;李岩;秦兰萍;吴兆苏
【期刊名称】《中华流行病学杂志》 【年(卷),期】2010(031)004
【摘要】Objective To explore the association between risk factors of cardiovascular diseases (CVD) and insulin resistance in a cross-sectional study.Methods An investigation on risk factors of CVD was carried out using stratified-random sampling method among 1475 participants in Beijing.Homeostasis model assessment index(HOMA) was calculated to assess the insulin resistance in 1359 non-diabetic subjects aged 25-64 years.Insulin resistance was defined as HOMA index (fasting glucose in mmol/L×fasting insulin in mU/L/22.5) in the top quartile of the studied population.Results The degree of correlation between risk factors and natural logarithm of HOMA index in descending order were glucose,body
mass
index
(BMI),triglyceride
(
TG
),waist
circumstance,high density lipoprotein- cholesterol (HDL-C),uric
acid,diastolic blood pressure,systolic blood pressure and total cholesterol(TC) (all P＜0.01 ).After adjusting factors as sex and age,glucose
(r=0.49),BMI(r=0.44),TG
(r=0.44),waist
circumstance
(r=0.41),uric acid (r=0.33) and HDL-C (r=-0.32),the systolic blood pressure (r=0.20),diastolic blood pressure (r=0.18) and TC (r=0.16) were
北京地区1359名非糖尿病人群心血管病危险因素与胰岛素抵抗的关系研究
