三种器官功能不全评分系统对重症脓毒症患者的预后评估
骆晓攀;王海宏;胡双飞;吴水晶;谢郭豪;程宝莉;周晨;方向明
【期刊名称】《中华外科杂志》 【年(卷),期】2009(047)001
【摘要】Objective To compare multiple organ dysfunction score (MOBS), the sequential organ failure assessment (SOFA) and the logistic organ dysfunction score (LOBS) in predicting hospital mortality in severe sepsis. Methods Four hundred and three patients admitted to the ICU from December 2004 to November 2007 with a diagnosis of severe sepsis were enrolled in this study. Their MOBS, SOFA, LOBS and Acute Physiology and Chronic Health Evaluation (APACHE) Ⅱ at admission and the highest score during hospitalization were respectively recorded and collated in regard to mortality. The discrimination of three multiple organ dysfunction score systems were assessed by the areas under the receiver operating characteristic curves (AUC). Results The AUC of admission scores was 0. 811 for LOBS, 0. 787 for SOFA, 0. 725 for MOBS, and 0. 770 for APACHE Ⅱ in predicting hospital mortality. All maximum scores had better power of discrimination than the admission scores ( P < 0. 01 ). The power of discrimination of LOBS and SOFA were better than the MOBS, either the admission or the highest, respectively (P < 0. 01 ). However, no significant difference was observed between the LODS and the SOFA regarding mortality prediction (P > 0. 05 ). The AUC value