血管内皮生长因子、α-羟丁酸脱氢酶、β2-微球蛋白和乳酸
脱氢酶在非霍奇金淋巴瘤诊断及预后中的价值
朱明;徐吟亚
【期刊名称】《现代肿瘤医学》 【年(卷),期】2017(025)010 【摘要】Objective:To
study
vascular
endothelial
growth
factor(VEGF),alpha hydroxybutyric acid dehydrogenase(α-HBDH),beta 2-microglobulin(β2-MG)and lactate dehydrogenase(LDH)in the value of diagnosis and prognosis of non-Hodgkin's lymphoma.Methods:All 139 cases of NHL patients of hematology were detected the serum VEGF,α-HBDH,β2-MG and LDH level before and after treatment,analyze the correlation of VEGF,α-HBDH,β2-MG,LDH,with the gender,age,clinical stage,pathological
type
and
the
malignant
degree.Results:In
50.36%,35.25% of NHL patients VEGF,α-HBDH increased had an obvious correlation between β2-MG and LDH.Different stages patients with VEGF,α-HBDH,β2-MG had significant difference,and LDH had no significant difference.Between invasive and indolent NHL patients VEGF,α-HBDH,LDH level had significant difference,and there was no significant
difference
in
β2-MG.These
indicators
in
different
gender,age,did not show significant difference.Before and after 2~3 course of chemotherapy in patients with serum VEGF,α-HBDH,LDH level had significant difference,there was no significant difference before and