生骨再造散对激素性股骨头坏死家兔血脂的影响
张晓刚;王钢;邓沂;刘建军;邱桐;任远
【期刊名称】《中国骨伤》 【年(卷),期】2001(014)003
【摘要】目的研究生骨再造散对激素性股骨头坏死家兔血脂水平的影响。方法家兔45只,随机分为5组:空白对照组、模型组、生骨再造散组、生骨再造散加手术组和马氏补骨片组。用糖皮质激素造成家兔激素性股骨头缺血性坏死模型。造模6周开始,生骨再造散和生骨再造散加手术组灌胃生骨再造散(3.2g*kg-1*d-1);马氏补骨片组灌胃马氏补骨片(0.6g*kg-1*d-1);空白对照组和模型组灌胃等容量生理盐水。于造模第5周和给药第5周测各组家兔的胆固醇、甘油三酯和高密度脂蛋白。结果模型组与空白对照组相比,血清胆固醇、甘油三酯明显升高(P<0.01),高密度脂蛋白明显降低(P<0.01);三个治疗组与模型组比较,血清胆固醇、甘油三酯明显降低(P<0.05),高密度脂蛋白明显升高(P<0.05);生骨再造散两组与马氏补骨片组比较无显著性差异。结论生骨再造散对股骨头坏死的治疗作用可能与其对血脂的调节作用有关。%Objective To explore the effects of Shengguzaizao San(SGZZS)(a prescription of traditional Chinese medicine on blood-lipid in models of hormoneinduced femoral head necrosis in rabbits.Methods 45 rabbits were divided into 5 groups randomly:1.control herbs)group;4.SGZZS Pian(MSBGP)(Chinese
group;2.model and
operation
group;3.SGZZS(Chinese group
and
5.Mashibugu
head
herb)group.Hormoneinduced femoral
necrosis models were produced by glucocorticoid hormone.From the
生骨再造散对激素性股骨头坏死家兔血脂的影响
