C反应蛋白是一种由肝脏合成的急性时相反应蛋白,是系统性炎症的非特异性标志,在炎性反应或组织损伤时急性期急剧升高,病情好转时很快下降,在有组织损伤及炎症情况下,特别是细菌性感染时其反应最为敏感。C反应蛋白是反映机体感染的敏感指标之一,不仅是多种疾病的标志物,也与疾病的发生发展有关,在一定程度上反映病理损伤的性质、范围和严重程度,对临床感染性疾病的诊断、监测及预后观察有重要价值。
C反应蛋白是一种敏感的急性时相反应蛋白,是一种在炎症肿瘤过程和手术后产生的炎性分子,主要是白细胞介素刺激肝脏和上皮细胞合成和蜂蜜的急性反应蛋白,属分泌型蛋白,在各种急性和慢性感染、恶性肿瘤、梗死、免疫复合物的沉着、手术、放射线等导致组织损伤时,通过细胞因子和其他介质介导的机体急性时相反应中,C反应蛋白在肝细胞中合成增加并与组织损伤程度成线性关系,在发病初期迅速升高,病情好转时有迅速至正常,此外,C反应蛋白不受性别、年龄、贫血、高球蛋白血症、发热、放疗、化疗的影响,是一个具有较高临床应用价值的指标。
C反应蛋白作为一种敏感的炎性反应标志物,它的升高可以提示许多炎性反应事件的发生,且升高程度常与炎性反应、组织损伤的程度呈正相关,在传染病的临床应用中前景将更加广阔。
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C-reactive protein is a kind of acute phase reactive protein synthesized by liver, which is a nonspecific sign of systemic inflammation. It rises sharply in acute stage when inflammatory reaction or tissue injury occurs, and drops quickly when the condition improves. It is most sensitive when there is tissue injury and inflammation, especially bacterial infection. C-reactive protein is one of the sensitive indicators to reflect infection, which is not only a marker of many diseases, but also related to the
occurrence and development of diseases. To a certain extent, it reflects the nature, scope and severity of pathological damage, and has important value for the diagnosis, monitoring and prognosis observation of clinical infectious diseases.
C-reactive protein is a sensitive acute phase reactive protein, which is an inflammatory molecule produced during the process of inflammatory tumor and after operation. It is mainly an acute phase reactive protein that stimulates the synthesis of liver and epithelial cells by interleukin and honey. It is a secretory protein. When various acute and chronic infections, malignant tumors, infarction, deposition of immune complexes, tissue damage caused by surgery, radiation, etc., in the acute phase reaction of the body mediated by cytokines and other media, The synthesis of C-reactive protein in liver cells increased linearly with the degree of tissue injury, and it increased rapidly at the early stage of the disease, and quickly reached normal when the disease improved. In addition, C-reactive protein was not affected by gender, age, anemia, hyperglobulinemia, fever, radiotherapy and chemotherapy, and was an index with high clinical application value.
C-reactive protein, as a sensitive marker of inflammatory reaction, can prompt many inflammatory reaction events, and its rising degree is often positively correlated with the degree of inflammatory reaction and tissue damage, which will have a broader prospect in clinical application of infectious diseases.
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