中国HIV-1急性期感染25例患者临床特点分析
李宁;郭伏平;李冠群;韩扬;谢静;李雁凌;祝婷;李太生
【期刊名称】《中华内科杂志》 【年(卷),期】2015(054)010
【摘要】Objective To summarize the clinical features,immunological and virological characteristics of HIV-1 infected patients in the acute phase for the sake of improving the understanding of acute HIV-1 infection and early diagnosis.Methods To retrospectively analyze the clinical manifestation and laboratory data of 25 patients with acute HIV infection,who were admitted to the Department of Infectious Diseases,Peking Union Medical College Hospital from 2006 to 2013.Results Among the total 25 patients,19 (76%) patients were sexually
transmitted,including
17
(68%)
of
whom
were
homosexual.Twenty two (88%) patients presented significant symptoms.Common
symptoms
consisted
of
fever
(15
patients,60%),cervical lymphoadenopathy (8 patients,32%),skin rashes (6 patients,24%),diarrhea (5 patients,20%),shortness of breath (3 patients,12%),sore throat (3 patients,12%),and cough (3 patients,12%),while only one case represented as Guillain-Barré syndrome,upper arm cellulitis,headache and vomiting,and perianal abscess.Laboratory lymphocytes
(13
examination
indicated
elevated liver
peripheral
(11
patients,52%),abnormal function