幽门螺杆菌感染与2型糖尿病并发症关系的临床研究
彭卫平;吴春松;叶晓莲;唐素琼;黄登鹏
【期刊名称】《中国医师进修杂志》 【年(卷),期】2013(036)022
【摘要】Objective To investigate the relationship between Helicobacter prlori (Hp) infection and type 2 diabetes related complications.Methods Eighty-five patients with type 2 diabetes had been tested and divided into Hp negative group (42 cases) and Hp positive group (43 cases),the triglyceride (TG),low density lipoprotein cholesterol (LDL-C),fasting plasma glucose (FPG),glycosylated hemoglobin (HbA1c),tumor necrosis factor-α (TNF-α) and complications occurred were compared between two groups.Results The TG,LDL-C,FPG,HbA1c and TNF-α in Hp positive group was significantly higher than that in Hp negative group [(4.83 ± 0.95) mmol/L vs.(3.03 ± 0.75) mmol/L,(4.99 ± 0.96) mmol/L vs.(3.91 ±0.87)mmol/L,(10.85 ±2.97) mmol/L vs.(8.11 ±2.69) mmol/L,(9.35 ± 1.96)% vs.(7.08 ± 1.53)%,(7.33 ± 0.78) ng/L vs.(3.65 ± 0.98) ng/L] (P< 0.01).The
cardiovascular
disease,cerebrovascular
disease,kidney
disease,retinal changes and podiatric complication rate in Hp positive group was 51.16% (22/43),37.21%(16/43),27.91%(12/43),34.88%(15/43),23.26%(10/43),significantly higher than that in Hp negative group [28.57% (12/42),16.67% (7/42),9.52% (4/42),14.29% (6/42),7.14% (3/42)],there was significant difference between two groups (P <