Relevant Factors of Estrogen Changes of Myopia in
Adolescent Females
Juan-Fen Gong;Hong-Li Xie;Xin-Jie Mao;Xue-Bo Zhu;Zuo-Kai Xie;Hai-Hong Yang;Yang Gao
【期刊名称】《中华医学杂志（英文版）》 【年(卷),期】2015(128)005
【摘要】Background:Gender is one of the risk factors accounting for the high prevalence of adolescent myopia.Considerable research results have shown that myopia incidence of female is higher than that of male.This study aimed to analyze the correlation between ocular parameters and serum estrogen level and to investigate the vision changes along with estrogen change in menstrual cycle of adolescent females.Methods:A total of 120 young females aged between 15 and 16 years,diagnosed with myopia were recruited.Spherical lens,cylindrical lens,axis,interpupillary distance (IPD),and vision in each tested eye of the same subject were measured by automatic optometry and comprehensive optometry,with repetition of all measurements in the menstrual cycle of the 2nd or 3rd days,14th days,and 282 days,respectively.Serum estradiol (E2) levels were assayed by chemiluminescence immunoassay at the same three times points of the menstrual cycle mentioned above.Results:In young females with myopia,the spherical lens showed a statistically significant difference
Relevant Factors of Estrogen Changes of Myopia in Adolescent Females
