一日法99Tcm-替曲膦运动-静息门控心肌灌注显像的临床
研究
王瑞华;孙珂;阮翘;孙秉奇;韩星敏;杜晓光;刘保平
【期刊名称】《中华核医学与分子影像杂志》 【年(卷),期】2012(032)005
【摘要】Objective To investigate the feasibility of 99Tcm-tetrofosmin G-MPI with a one-day stress/rest protocol in subjects suspected with coronary heart disease (CHD).Methods Fifty-two subjects who had undertaken 99Tcm-tetrofosmin myocardial SPECT and CAG because of suspected CHD were retrospectively analyzed.The patients were divided into a coronary artery stenosis group and a normal group according to CAG results.Exercise and rest G-MPI was performed using a one-day protocol with the interval of exercise and rest imaging at (129 ±4) min.SPECT acquisition started at about 30 min after tracer administration.In addition,during stress imaging,dynamic anterior planar imaging (from 1-30 min after tracer injection) and a planar image at 2 h were acquired.Radioactivity in the left ventricle myocardium,liver and chest was analyzed using ROI technology.Left ventricle myocardial segment perfusion and left ventricle function were evaluated with Cedars myocardial quantitative assessment software.The parameters of left ventricle function (LVEF,EDV and ESV) obtained from G-MPI were compared with that from ultrasonic cardiogram using a paired t