Use of MIF and MIF pathway agonists
申请(专利)号: US201715648956
专利号: US10765739B2 主分类号: C12N15/62
申请权利人: YALE UNIVERSITY
公开国代码: US 优先权国家: US
摘 要:
The present invention relates to novel methods and compositions for increasing AMPK activity and glucose uptake
comprising administering a macrophage migration inhibitory factor (MIF) pathway agonist in a subject in need thereof. The invention also relates to methods for selecting a subject for treatment with an agonist of MIF, identifying a subject at risk for developing a condition in which
increased AMPK activity is desirable, and for predicting whether a subject is
申请日: 2017-07-13 公开公告日: 2020-09-08
分类号: C12N15/62;
A61K39/395; C07K14/52; C12Q1/6883; A61K31/7088 发明设计人: RICHARD BUCALA;
LAWRENCE H. YOUNG 申请国代码: US
优先权: 20170713 US
201715648956; 20130128 US 201313751887; 20080403 US 8313108; 20061006 US 2006039315; 20051007 US 72514605; 20051129 US 74042205
摘 要 附 图:
susceptible to a condition in which increased AMPK activity is desirable. 主权项:
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