18F-FDG PET-CT代谢参数与乳腺癌临床病理特征的关系
汤泊;张银;周锦;徐阳;李天女;丁重阳
【期刊名称】《中华肿瘤杂志》 【年(卷),期】2017(039)004
【摘要】Objective To investigate the relationship between metabolic parameters of primary lesion and clinicopathological features of patients with breast cancer.Methods Clinical data of 78 patients with breast cancer undergone 18F-FDG PET/CT before surgery was retrospectively analyzed.SUVmax, SUVmean and metabolic tumor volume (MTV) of primary lesions were measured by horizontal, sagittal and coronal position volume section with a threshold of 40% SUVmax.TLG was calculated and the highest SUVmax among metastatic lymph nodes was measured.Results SUVmax, SUVmean, MTV, TLG and the maximum diameter of 78 primary lesions were 6.64(1.85, 22.79), 3.88(1.30, 11.42), 13.36(1.66, 129.08)cm3, 47.92(2.85, 443.28)g and 2.35(1.23, 9.80)cm, respectively.SUVmax of metastatic lymph node was 5.12(2.38, 14.32).There were statistically significant differences of primary lesion metabolic parameters (SUVmax, MTV, TLG) in different pathological stages,T stages, with or without lymph node invasion (all P<0.05).Only TLG of ER negative patients was higher than that of ER positive patients (P<0.05).TLG, MTV of PR negative patients were higher than that of PR positive patients (both P<0.05).No significant