儿童非霍奇金淋巴瘤195例临床病理分析
王佳;奚政君;李稻
【期刊名称】《临床儿科杂志》 【年(卷),期】2011(029)011
【摘要】Objective To evaluate the clinical and pathological features of childhood non-Hodgkin's lymphoma (NHL). Methods A total of 195 NHL cases, with age younger than twelve years old, diagnosed from January 1982 to January 2010 in Xinhua Hospital were reviewed. Results The peak onset age is 6 - 8 years old. The male to female ratio is 2.3 : 1 and male patients predominate in each subtype. The cases in stage III and IV account for 49.2%. The most common subtypes were lymphoblastic lymphoma (LBL) , Burkitt lymphoma (BL) and anaplastic large cell lymphoma (ALCL). About 88.8% cases of LBL is T-cell lymphoma while all the BL is B-cell lymphoma and all the ALCL is T-cell lymphoma. More than 1/3 (37.9%) of all the cases have primary extranodal lymphoma. More than one organ involvement was found in 56.1% of LBL cases when they were diagnosed. Conclusions Childhood NHL differs greatly from adult NHL in clinical and pathological aspects. Immunohistochemistry plays an important role in diagnosis.%目的 探讨儿童非霍奇金淋巴瘤(NHL)的临床病理特点.方法 收集1982年1月-2010年1月诊断的非霍奇金淋巴瘤病例195例,进行临床和病理分析.结果 儿童NHL发病年龄高峰在6～8岁,男女之比为2.3:1,III期和IV期占49.2%.病理组织类型
主要有淋巴母细胞性淋巴瘤(LBL)、Burkitt淋巴瘤(BL)、间变性大细胞性淋巴瘤(ALCL);88.8%LBL为T细胞性淋巴瘤,BL皆为B细胞性淋巴瘤,ALCL皆为T细胞性淋巴瘤.37.9%病例首发于淋巴结外组织,56.1%LBL患儿确诊时已累及1个以上部位.结论 儿童NHL的临床及病理表现与成人NHL存在很大差异.免疫组化等技术对NHL的病理诊断有重要作用. 【总页数】3页(1060-1062)
【关键词】非霍奇金淋巴瘤;临床病理学;回顾性研究;儿童 【作者】王佳;奚政君;李稻
【作者单位】上海交通大学医学院病理生理学教研室,上海,200025;上海交通大学医学院附属新华医院病理科,上海,200092;上海交通大学医学院病理生理学教研室,上海,200025 【正文语种】中文 【中图分类】R733 【文献来源】
https://www.zhangqiaokeyan.com/academic-journal-cn_journal-clinical-pediatrics_thesis/0201235725677.html 【相关文献】
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儿童非霍奇金淋巴瘤195例临床病理分析
