奥氮平联合元认知训练治疗精神分裂症对照研究
张腾;何益群;申丽娟
【期刊名称】《临床心身疾病杂志》 【年(卷),期】2017(023)003
【摘要】目的 探讨奥氮平联合元认知训练对精神分裂症患者临床疗效、自知力及治疗依从性的影响.方法 将120例精神分裂症患者采用随机数字表法分为两组,均口服奥氮平治疗,研究组联合元认知训练治疗,观察4周.于治疗前及治疗4周末分别采用阳性与阴性症状量表、自知力及治疗态度问卷及药物依从性评定量表对两组患者进行评定. 结果 治疗4周末两组阳性与阴性症状量表总分及各因子分均较治疗前显著下降(P<0.01),研究组较对照组下降更显著(P<0.01);两组自知力及治疗态度问卷及药物依从性评定量表评分均较治疗前显著上升(P<0.01),研究组较对照组上升更显著(P<0.01).在临床疗效方面,研究组总有效率显著高于对照组(P<0.01).结论 奥氮平联合元认知训练治疗精神分裂症疗效显著,能够改善患者的自知力,提高治疗依从性.%Objective To explore the effects of olanzapine plus metacognitive training (MCT) on efficacy, insight and
medication
adherence.Methods
A
total
of 120
schizophrenics were assigned to two groups, both groups were treated with olanzapine, and research group was plus MCT for 4 weeks.Assessments were performed with the Positive and Negative Syndrome Scale (PANSS), Insight and Treatment Attitude Questionnaire (ITAQ) and Medication Adherence Rating Scale (MARS) at baseline and at the end of the 4th week treatment.Results At the end of the 4th week
奥氮平联合元认知训练治疗精神分裂症对照研究
