前哨淋巴结活检在cN0口腔鳞状细胞癌治疗中的临床意义
刘建伟;曹钟义;钱永;危由春;习伟宏
【期刊名称】《医学信息》 【年(卷),期】2014(000)038
【摘要】目的探讨前哨淋巴结活检在cN0口腔鳞状细胞癌治疗中的可行性、准确性。方法对20例cN0口腔鳞状细胞癌患者术前使用核素扫描法行前哨淋巴结示综,体表定位;术中r原探测仪垣亚甲蓝染色进一步识别前哨淋巴结,行前哨淋巴结活检,同时行颈部淋巴清扫,术后对前哨淋巴结和颈部非前哨淋巴结的病理检查结果进行分析。结果20例cN0口腔癌患者共检测出38枚前哨淋巴结,前哨淋巴结检测率100%,常规病理检查阳性率(21枚/38枚)55.3%,另外17枚阴性前哨淋巴结加行免疫组化(CK法)检查阳性率(2枚/17枚)11.8%。结论前哨淋巴结活检是cN0口腔鳞状细胞癌治疗中的一项新技术,能较准确地反映颈部淋巴结状态,具有一定的临床实用性。%Objective To explore the feasibility and reliability of sentinel lymph node biopsy in the treatment of cN0 oral squamous cel carcinoma. Methods Radionuclide scanning was used to trace and locate the sentinel lymph node in 20 patients with cN0 oral squamous cel carcinoma before operation. And during surgery, sentinel lymph node biopsy and cervical dissection were conducted after the sentinel lymph node had been further identified by using γ-detector and methylene blue staining. At last, the sentinel lymph node and non-sentinel lymph nodes of the neck were pathological y diagnosed and analyzed after operation. Results Al of the
20 patients of cN0 oral cancer were detected to be with sentinel lymph node (in total 38 pieces). 21 of the 38 sentinel lymph nodes (55.3%) were found to be with cancer cel matastasis by routine pathological examination. The other 17 negative nodes were put into immunohistochemistry staining (CK) and 2 were confirmed to be positive (11.8%). Conclusion As a newtechnique in the treatment of oral squamous cel carcinoma, sentinel lymph node biopsy is able to accurately reflect the status of cervical lymph node and is with certain value of clinical application. 【总页数】2页(22-23)
【关键词】前哨淋巴结;口腔鳞状细胞癌;淋巴转移;淋巴闪烁显像 【作者】刘建伟;曹钟义;钱永;危由春;习伟宏
【作者单位】南昌大学第一附属医院口腔颌面外科,江西 南昌 330006;南昌大学第一附属医院口腔颌面外科,江西 南昌 330006;南昌大学第一附属医院口腔颌面外科,江西 南昌 330006;南昌大学第一附属医院口腔颌面外科,江西 南昌 330006;南昌大学第一附属医院口腔颌面外科,江西 南昌 330006 【正文语种】中文 【中图分类】 【文献来源】
https://www.zhangqiaokeyan.com/academic-journal-cn_medical-information_thesis/0201252482421.html 【相关文献】
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