In vivo anti-inflamatory potential of various extracts of Sida tiagii Bhandari

In vivo anti-inflamatory potential of various

extracts of Sida tiagii Bhandari

Suresh Kumar

【期刊名称】《亚太热带生物医学杂志（英文版）》 【年(卷),期】2012(000)0z2

【摘要】Objective: The present study is an attempt to explore the anti-inflammatory activity of n-Hexane extract (HS), Ethyl acetate extract (EAS) and Residual ethanolic extract (RES) of fruits of Sida tiagii Bhandari by using carrageenan and egg-albumin induced paw edema, xylene induced ear edema and cotton wool granuloma animal models. Methods: The biochemical markers like or lysosomal enzymes viz. serum glutamic oxaloacetic transaminase (SGOT), serum glutamic pyruvic transaminase (SGPT) and alkaline phosphatase (ALP) were also found out in blood serum. Results:There was decrease in edema volume in EAS and RES administered animals in carrageenan and egg-albumin induced edema models. The percentage inhibition of inflammation in EAS (34.15%) and RES (39.66%) was found comparable with that of the standard drug, diclophenac sodium (46.69%). The two extracts EAS and RES was found to have good anti-inflammatory activity as compared to standard drug. Conclusions: Thus the plant can be used as a potential anti-inflammatory candidate in animals. 【总页数】6页(947-952)

【关键词】

【作者】Suresh Kumar

【作者单位】Department of Pharmaceutical Sciences,Guru Jambheshwar University of Science and Technology, Hisar-125001, India 【正文语种】英文 【中图分类】 【文献来源】

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