Schizophrenia susceptibility genes on chromosome
13q32
胡颖;许琪;鞠桂芝;刘树铮;史杰萍;于雅琴;尉军
【期刊名称】《中华医学杂志（英文版）》 【年(卷),期】2004(117)003
【摘要】@@Schizophrenia is a complex mental disorder affecting approximately 1% of the general population worldwide.1 It has a high incidence in the general population, a poor prognosis and a poor outcome, in that it has become a major social problem. Family, twin, and adoption studies have clearly shown that a genetic component is quite likely to play an important role in determining susceptibility to schizophrenia.
The
genome-wide
scan
indicates
that
several
chromosomal regions are linked to schizophrenia, some of which have been replicated independently including 6p21-24, 8p21-22, 13q14-33 and 22q11-12.2,3 This study was designed to detect two single nucleotide polymorphisms (SNPs) located in the 13q14-33 region, rs188608 at the STK24 locus and rs2892679 at the GPC6 locus, among Chinese population. 【总页数】3页(464-466)
【关键词】schizophrenia;susceptibility gene;single nucleotide polymorphism
【作者】胡颖;许琪;鞠桂芝;刘树铮;史杰萍;于雅琴;尉军
Schizophrenia susceptibility genes on chromosome 13q32
