Expression and clinical significance of the genes of Hedgehog signaling pathway in sporadi
Expression and clinical significance of the genes of
Hedgehog signaling pathway in sporadic keratocystic odontogenic tumor of the jaw bones
Kong Li;Yuan Rong-tao;Jia Mu-yun;Wang Ke;Wang Bingchao;Yang Yinhui
【期刊名称】《医学美学美容（中旬刊）》 【年(卷),期】2015(000)002
【摘要】PURPOSE It was to study the role of genes of Hedgehog signaling pathway in sporadic keratocystic odontogenic tumor (KCOT)of the jaw bones.METHODS Fresh specimens of sporadic KCOT and the same patient 's normal oral mucosa were obtained.Then RNA was extracted.Gene chip was used to detect the genes of Hedgehog signaling pathway.RESULTS Com-pared to normal oral mucosa,there were five genes of Hedgehog signaling pathway in KCOT changed,including PRKX ,WNT5a,PTCH1 up -regulated.CONCLUSION There were abnormal ex-pressions of genes of Hedgehog pathway in sporadicKCOT.Genes of Hedgehog pathway played roles in sporadic KCOT.
【总页数】1页(666-666) 【关键词】
【作者】Kong Li;Yuan Rong-tao;Jia Mu-yun;Wang Ke;Wang Bingchao;Yang Yinhui
【作者单位】Department of 0ral and Maxillofacial Surgery,the Affiliated
Expression and clinical significance of the genes of Hedgehog signaling pathway in sporadi
