Endogenous enkephalin does not contribute to the cerebral anti-hyperalgesic action of gabapentin

Endogenous enkephalin does not contribute to the cerebral anti-hyperalgesic action of gabapentin

佚名

【期刊名称】《中国科学》 【年(卷),期】2010(000)012

【摘要】The aim of this study was to investigate the role of endogenous enkephalin

in

the

cerebral

antihyperalgesic

action

of

gabapentin.Neuropathic pain models and antihyperalgesic effect of gabapentin were confirmed by the presentation and changes of mechanical allodynia and thermal hyperalgesia of operated mouse hind paws.The results suggested that endogenous enkephalin may not be involved in the antihyperalgesic effect of gabapentin. 【总页数】5页(P.1428-1432)

【关键词】neuropathic;pain;gabapentin;enkephalin;cerebral;cortex 【作者】佚名 【作者单位】; 【正文语种】英文 【中图分类】Q 【相关文献】

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