MACC1在消化系统肿瘤中的研究进展
刘思诗;耿敬姝
【期刊名称】《现代肿瘤医学》 【年(卷),期】2018(026)004
【摘要】MACC1是新近发现的与癌症的发生和发展密切相关的基因,一些细胞信号转导通路或生物分子可能参与了MACC1的表达调控以及MACC1促进肿瘤侵袭转移的相关机制.由于MACC1在消化系统肿瘤中的高表达,可能使其成为新的判断肿瘤预后和治疗的靶点.本文就消化系统肿瘤中MACC1的研究进展进行综述.%MACC1 was recently identified a key gene controlling tumor growth and metastasis.Some cell signaling pathways or biological molecules may be involved in the regulation of MACC1 expression and relevant mechanism of MACC1 promoting tumor invasion and metastasis.As a result of MACC1 in high expression of digestive system tumors,MACCI may become the new judging tumor prognosis and therapeutic targets.The recent progress of MACC1 research in digestive system neoplasms was reviewed in this article. 【总页数】4页(630-633)
【关键词】MACC1;消化系统肿瘤;预后;转移;侵袭 【作者】刘思诗;耿敬姝
【作者单位】哈尔滨医科大学附属肿瘤医院,黑龙江哈尔滨150081;哈尔滨医科大学附属肿瘤医院,黑龙江哈尔滨150081 【正文语种】中文