乙肝肝硬化患者的抗病毒治疗
陈焕永;张新
【期刊名称】《医学与哲学》 【年(卷),期】2011(032)022
【摘要】Liver cirrhosis is one of the final outcomes of hepatitis B infection. Studies have demonstrated that anti-HBV therapy, including interferon and nucleosides/nucleotides analogues, can lead to histological improvement, and even complete reversibility of liver cirrhosis, a long-term or even life-long treatment is needed. Therefore, the treatment of hepatitis B virus - induced cirrhosis should be abided by individual therapeutic principles, according to the patient's condition, drug characters/side effects and cost-effectiveness. More effective, safe and affordable anti-HBV agents are needed for these populations.%乙肝肝硬化是HBV感染的最终结局之一.目前的研究证明,抗病毒治疗能使肝脏组织学获得改善甚至逆转肝硬化的病情.多种核苷(酸)类似物及干扰素的临床应用,使乙肝肝硬化的抗病毒治疗取得较大进展,但患者仍需长期甚至终生治疗.因此,应遵循个体化的治疗原则,针对患者病情、药物特点、不良反应、患者经济承受能力,选择强效、低耐药且较经济的治疗方案以获得最佳疗效. 【总页数】5页(8-11,47)
【关键词】肝硬化;乙型肝炎病毒;抗病毒治疗 【作者】陈焕永;张新
【作者单位】哈尔滨医科大学附属第一医院感染科 黑龙江哈尔滨150001;哈尔
乙肝肝硬化患者的抗病毒治疗
