2型糖尿病视网膜病变患者脑部视觉中心损伤的MR弥散
加权成像研究
王中领;葛晓敏;钱农;李晶;陆紫微;陈罕奇;戴伊红
【期刊名称】《中华神经医学杂志》 【年(卷),期】2014(013)007
【摘要】Objective To investigate the possible brain diffusion changes in different sites of the brain,particularly in areas associated with vision function,of patients with proliferative and nonproliferative retinopathy by using diffusion-weighted imaging (DWI).Methods Forty-five type 2 diabetic patients,admitted to our hospital from March 2012 to March 2013,were
chosen
in
our
study;according
to
the
fundus
examination,they were divided into group of proliferative retinopathy (n=15) group of non-proliferative retinopathy (n=15) and group of no retinopathy (n=15); another 15 healthy controls were chosen.T2WI and DWI with 3.0T magnetic resonance imaging (MRI) were performed; the apparent diffusion coefficient (ADC) values in the orbitofrontal cortex,cingulated gyrus,thalamus,dorsomedial and dorsolateral frontal cortex,and corona radiate were calculated; and then,Spearman's correlation analysis was performed between ADC values and both course of disease and glycosylated hemoglobin level.Results The ADC values of orbitofrontal cortex,cingulated gyrus and visual cortex in groups of proliferative and non-proliferative retinopathy were
2型糖尿病视网膜病变患者脑部视觉中心损伤的MR弥散加权成像研究
