复方丹参片联合胸腺法新治疗失代偿期丙型肝炎肝硬化的
疗效观察
赵宝生;董金玲;谢放;张龙;温慧敏
【期刊名称】《现代药物与临床》 【年(卷),期】2017(032)002
【摘要】Objective To study the clinical effect of Compound Danshen Tablets combined with Thymalfasin for injection in treatment of decompensated hepatitis C cirrhosis.Methods Patients (120 cases) with decompensated hepatitis C cirrhosis in CNPC Central Hospital and Beijing You'an Hospital, Capital Medical University from October 2013 to May 2014 were divided into control and treatment groups, and each group had 60 cases. Patients in the control group were ivadministered with Thymalfasin for injection, 1.6 mg/time, twice one week. Patients in the treatment group werepoadministered with Compound Danshen Tablets on the basis of the control group, 3 tablets/time, three times daily. Patients in two groups were treated for 12 months. After treatment, the clinical efficacy was evaluated, liver function and fibrosis indexes, HCV-RNA level, Child-Pugh score and HBeAg negative conversion rate in two groups before and after treatment were compared.Results After treatment for 12 months, TBiL and ALT levels in two groups were significantly decreased, but ALB level was increased, the difference was statistically significant in the same group (P < 0.05).