血尿酸水平对原发性高血压患者血清高敏C反应蛋白水平、
血压变异性的影响
陈益飞;李旭东
【期刊名称】《中国血液流变学杂志》 【年(卷),期】2013(000)001
【摘要】 目的探讨高尿酸血症对原发性高血压患者血清高敏C反应蛋白（hs-CRP）水平及血压变异性（BPV）的影响。方法将确诊的99例原发性高血压患者根据血尿酸水平分为尿酸正常组（NUA组）和高尿酸组（HUA组），进行24h动态血压检查、血清hs-CRP检测，观察比较两组血清hs-CRP、24h、昼间、夜间收缩压变异性（SBPV）和舒张压变异性（DBPV）。结果 HUA组血清hs-CRP水平、收缩压变异性均较NUA组增高。结论高尿酸血症可促使原发性高血压患者血清hs-CRP水平和收缩压变异性升高，推测高尿酸血症是血压变异性增加的独立危险因素，通过炎症反应途径导致血压变异性增加。%Objective To evaluate the effects of serum uric acid on high sensitive c-reactive protein(hs-CRP) and blood pressure variability(BPV) in patients with hypertension.Method According to levels of serum uric acid,the total of 99 hypertension patients were divided into two groups:normal uric acid group(NUA group) and high uric acid group(HUA group).All the patients were given 24-hour ambulatory blood pressure monitoring and measured serum hs-CRP,the level of hs-CRP as well as systolic and diastolic BP variability obtained during 24-hour,daytime and nighttime were compared in both groups.Result
血尿酸水平对原发性高血压患者血清高敏C反应蛋白水平、血压变异性的影响
